High-grade Giloma
Conditions
Interventions
Chinese Guideline:delineating basis of Chinese Guideline
T2 FLAIR:delineating basis of T2 FLAIR sequence
Chinese Guideline+boosting:delineating basis of Chinese Guideline and boosting
T2 FLAIR+boosting:delineating basis of T2 FLAIR sequence and boosting
Sponsors
ZHONG YAHUA
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. signature of informed consent voluntarily; 2. Pathological diagnosis of high-grade glioma (including anaplastic glioma of WHO III and glioblastoma of WHO IV grade); 3. Aged 18-65 years old, male and female, PS score 0-2; no basic disease or well-controlled patients; 4. Normal blood-routine test: WBC > 3.5x10^9/L, GRAN > 2.9 x10^9/L; Hb > 90g/L, PLT > 100 x10^9/L; 5. Normal liver function: serum creatinine was less than 1.5xULN, and creatinine clearance rate was more than 60 ml/min.
Exclusion criteria
Exclusion criteria: 1. patients unwilling to participate in the experiment or have poor compliance; 2. other clinical trials being conducted; 3. previous history of brain tumor and radiotherapy conducted; 4. multiple lesions with extensive radiation volume; 5. With history of radiotherapy for brain tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival; | — |
Countries
China
Contacts
Public ContactZHONG YAHUA
Zhongnan Hospitol of Wuhan University
Outcome results
None listed