NSCLC
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Men or women aged 18 to 75 years old; 2. Planned radical resection of lung cancer with intraoperative hihar and mediastinal lymph nodes dissection along the vagus nerve and phrenic nerve chain; 3. Intraoperatie and/or postoperative histopathology confirmed as R0 resected non-small cell lung cancer (NSCLC); 4. Obtain informed consent signed by the patient or his legal representative; 5. Good compliance; 6. ECOG behavior status score 0~1.
Exclusion criteria
Exclusion criteria: 1. Have cancer other than NSCLC within five years prior to the study; 2. Known human immunodeficiency virus (HIV) infection; 3. With small cell lung cancer components; 4. Pregnant or lactating women; 5. Have a clear history of neurological or mental disorders, including epilepsy or dementia; 6. neoadjuvant chemoradiation before surgery; 7. Other situations investigators believe that it is not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pathological N-stage up-regulation rate;postoperative quality of life; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vagus nerve injury score;Phrenic nerve injury score;the number of lymph node dissection groups;OS;DFS;Perioperative complications;the number of dissected lymph nodes; | — |
Countries
China
Contacts
The First Affiliated Hospital of Sun Yat-sen University