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Targeted Cellular Immunotherapy for HPV-specific Cytokine-induced Killer Cells

Targeted Cellular Immunotherapy for HPV-specific Cytokine-induced Killer Cells

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018828
Enrollment
Unknown
Registered
2018-10-12
Start date
2017-10-01
Completion date
Unknown
Last updated
2018-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HPV infection caused by cervical cancer, cervical intraepithelial neoplasia lesions, polyps, warts, etc.

Interventions

Case series:Targeted Cellular Immunotherapy

Sponsors

Hefei Ruichengsheng Biotechnology Co., Ltd.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients' HPV test should be positive and should be determine which HPV subtype the patient was (or were) infected with. While meeting this condition, patients should also following the requirements: (1) not having a serious autoimmune disease; (2) not having T lymphoma; (3) being unable to be allergic to cytokines; (4) non-lactation and pregnancy; (5) not suffering There are serious infectious diseases; (6) organ function is not exhausted; (7) there is no history of organ transplantation.

Exclusion criteria

Exclusion criteria: (1) the patient has a negative HPV DNA test; (2) the patient has a severe autoimmune disease; (3) the patient has a T lymphoma; (4) the patient is allergic to cytokines; (5) the patient is During treatment, during lactation and pregnancy; (6) the patient has a serious infectious disease; (7) the patient's organ failure; (8) the patient has had a history of organ transplantation.

Design outcomes

Primary

MeasureTime frame
HPV positive to negative;Specific CTL;Cytokines such as IL-2 and IFN-?;Cell subgroups such as CD4+, CD8+, CD3+CD56+ cells;

Countries

China

Contacts

Public ContactJU ZHANG

Hefei Ruichengsheng Biotechnology Co., Ltd.

jianzhong@fmmu.edu.cn+86 13119191036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026