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Study for oxytocin dose-effect relationship during cesarean section of scarred uterus and elderly scarred uterus

Study for oxytocin dose-effect relationship during cesarean section of scarred uterus and elderly scarred uterus

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018779
Enrollment
Unknown
Registered
2018-10-09
Start date
2018-10-15
Completion date
Unknown
Last updated
2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing elective cesarean section

Interventions

Nonscar uterus group:I.V. Oxytocin bolus or infusion (different dose)
Scar uterus group:I.V. Oxytocin bolus or infusion (different dose)
Elderly scar uterus group:I.V. oxytocin bolus or infusion (different dose)
Youth sar uterus group:I.V. oxytocin bolus or infusion (different dose)

Sponsors

Women and Children Hospital affiliated Jiaxing University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: ASA I or II, aged 18 to 50 years, singleton pregnancies, scarred uterus and the first time elective CD with a Pfannensteil incision. All enrolled patients received spinal anaesthesia and level of anesthesia is T4-T6.

Exclusion criteria

Exclusion criteria: Active labour, ruptured membranes, known drug allergy to oxytocin, multiple gestation, significant obstetric disease (including pregnancy-induced hypertension or pre-eclampsia), known risk factors for postpartum haemorrhage (including abnormal placentation, giant gestation, uterine fibroids, history of postpartum haemorrhage or uterine atony), inherited or acquired coagulation disorder, and thrombocytopenia (platelet count,100 *10^9).

Design outcomes

Primary

MeasureTime frame
oxytocin dosage;estimate blood loss;Adverse reaction;Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone;

Countries

China

Contacts

Public ContactWei Changna

Maternity and Child Affiliated Hospital, Jiaxing University

544631360@qq.com+86 18267382732

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026