Depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years old male and female outpatient; 2. Has a diagnosis of recurrent major depressive disorder by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria,with no psychotic symptoms; 3. the depressive episode has been treated with an SSRI antidepressant for 6 to 12 weeks; 4. hamd-17< 14 in screening; 5. the education level above primary school can understand the content of the scale; 6. the patient signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous clear episodes of mania or hypomania; 2. Previous diagnoses of bipolar disorder, schizophrenia, schizoaffective disorder and mental disorders associated with other diseases; 3. Patients currently have a high risk of suicide (the risk of suicide of MINI6.0.0 B module is severe, or the item of hamd-17 suicide risk is greater than or equal to 3 points); 4. MECT, transcranial magnetic stimulation, antipsychotics, non-benzodiazepines, mood stabilizers were used during the depressive episode; 5. Patients with a history of alcohol dependence and acute poisoning; 6. Female patients during pregnancy or lactation; 7. At present, researchers of severe somatic diseases think it is not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sustained response time; | — |
Secondary
| Measure | Time frame |
|---|---|
| relapse rate;compliance; | — |
Countries
China
Contacts
Beijing Anding Hospital Affiliated to Capital Medical University