The affect of granisetron to spontaneous contraction of human pregnant myometrium in vivo

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800018765

Enrollment

Unknown

Registered

2018-10-09

Start date

2018-10-01

Completion date

Unknown

Last updated

2018-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pregnancy

Interventions

experimental group:granisetron

control group:saline

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: parturients with American Society of Anesthesiologists physical status I or II, between 20 and 35 year, with singleton pregnancies, and undergoing an elective cesarean delivery with a Pfannenstiel incision and a spinal anesthetic technique.

Exclusion criteria

Exclusion criteria: parturients with the presence of labor, ruptured membranes, maternal or fetal risk factors for uterine atony (i.e., macrosomia, multiple gestations, chorioamnionitis, diabetes mellitus, and uterine fibroids), previous uterine surgery, maternal risks for hemorrhage (i.e., abnormal placentation, previous abdominal surgeries, history of previous peripartum hemorrhage, coagulation abnormalities, and thrombocytopenia <100 × 10^9), contraindications to spinal anesthesia or any of the uterotonic agents, and maternal or obstetrician refusal.

Design outcomes

Primary

Measure	Time frame
VAS;	—

Countries

China

Contacts

Public ContactXuemei Lin

West China Second Hospital

xuemeilin__scu@163.com+86 17380589827

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026