The effect of intravenous ondansetron 5 min before spinal induction on the dose-response of phenylephrine preventing spinal-induced hypotension in cesarean delivery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800018756

Enrollment

Unknown

Registered

2018-10-08

Start date

2018-10-10

Completion date

Unknown

Last updated

2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypotension

Interventions

Group O:ondansetron

Group S:saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria were healthy parturients with an ASA statue of I or II, single pregnant.

Exclusion criteria

Exclusion criteria: Patients with obesity (body mass index, BMI > 35 kg/m2), gestational age < 37 weeks, active labor, early labor, ruptured membranes, history of previous cesarean deliveries, diabetes or gestational diabetes, hypertension or pre-eclampsia, intrauterine growth restriction, placenta previa, significant coexisting maternal disease, any contraindication to spinal or epidural anesthesia such as local infection or bleeding disorders.

Design outcomes

Primary

Measure	Time frame
dose of phenylephrine;	—

Secondary

Measure	Time frame
side effects of anesthesia;Apgar score and blood gas analysis of umbilical arteries;characters of anesthesia;	—

Countries

China

Contacts

Public ContactXiao Fei

Jiaxing Maternity and Child Care Hospital/Jiaxing University Affiliated Women and Children Hospital

13706597501@163.com+86 13706597501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026