Skip to content

A randomized controlled trial for effects of estradiol at different levels on severe IUA after hysteroscopic adhesiolysis

A randomized controlled trial for effects of estradiol at different levels on severe IUA after hysteroscopic adhesiolysis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018749
Enrollment
Unknown
Registered
2018-10-07
Start date
2016-09-19
Completion date
Unknown
Last updated
2018-10-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine adhesions

Interventions

Case series:Nil

Sponsors

Beijing Obstetrics and Gynecology Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) Medical history: previous history of intrauterine surgery, menstrual changes including menstrual reduction, periodic lower abdominal pain, or amenorrhea, in the aspect of fertility can be secondary infertility, or repeated abortion, embryo suspension, etc.; (2) Hysteroscopy: according to the American Fertility Association intrauterine adhesion evaluation criteria (AFS evaluation criteria), diagnosed as severe intrauterine adhesions (9 to 12 points); (3) Aged 20 to 40 years old, with normal ovarian function; (4) No oral estrogen drug contraindications, such as a history of thrombotic disease, liver and kidney dysfunction; (5) No digestive system diseases affecting drug absorption; (6) Sign the informed consent form and be able to accept regular follow-up.

Exclusion criteria

Exclusion criteria: (1) Combined with pelvic acute and chronic inflammation or endometriosis, adenomyosis, men's semen abnormalities and other factors that may lead to infertility; (2) Those with metabolic or connective tissue disease; (3) Complications such as uterine perforation during intrauterine adhesion operation; (4) There was obvious infection after operation, body temperature =38 degree C, blood WBC=11.0×10^9/L.

Design outcomes

Primary

MeasureTime frame
Intrauterine adhesion score;

Secondary

MeasureTime frame
Menstrual volume;

Countries

China

Contacts

Public ContactChen Fang

Beijing Obstetrics and Gynecology Hospital, Capital Medical University

chenfang820918@163.com+86 13581582372

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026