Intrauterine adhesions
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Medical history: previous history of intrauterine surgery, menstrual changes including menstrual reduction, periodic lower abdominal pain, or amenorrhea, in the aspect of fertility can be secondary infertility, or repeated abortion, embryo suspension, etc.; (2) Hysteroscopy: according to the American Fertility Association intrauterine adhesion evaluation criteria (AFS evaluation criteria), diagnosed as severe intrauterine adhesions (9 to 12 points); (3) Aged 20 to 40 years old, with normal ovarian function; (4) No oral estrogen drug contraindications, such as a history of thrombotic disease, liver and kidney dysfunction; (5) No digestive system diseases affecting drug absorption; (6) Sign the informed consent form and be able to accept regular follow-up.
Exclusion criteria
Exclusion criteria: (1) Combined with pelvic acute and chronic inflammation or endometriosis, adenomyosis, men's semen abnormalities and other factors that may lead to infertility; (2) Those with metabolic or connective tissue disease; (3) Complications such as uterine perforation during intrauterine adhesion operation; (4) There was obvious infection after operation, body temperature =38 degree C, blood WBC=11.0×10^9/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intrauterine adhesion score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Menstrual volume; | — |
Countries
China
Contacts
Beijing Obstetrics and Gynecology Hospital, Capital Medical University