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Diagnostic value of pleural brushing combined with pleural effusion cell wax block technique in closed pleural biopsy in malignant pleural effusion: a prospective, open, randomized controlled clinical study

Diagnostic value of pleural brushing combined with pleural effusion cell wax block technique in closed pleural biopsy in malignant pleural effusion: a prospective, open, randomized controlled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018727
Enrollment
Unknown
Registered
2018-10-06
Start date
2018-11-01
Completion date
Unknown
Last updated
2018-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant pleural effusion

Interventions

Sponsors

Department of Respiratory Medicine, First Affiliated Hospital of Army Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18-80 years old; 2. Clinical diagnosis and chest CT and other imaging examinations considered as malignant pleural effusion; 3. The pleural effusion can be positioned by ultrasound, and the thickness is =3cm; 4. Patient without other serious cardiopulmonary disease; 5. Patients without invasive contraindications such as thoracentesis and pleural biopsy; 6. Patients and their families agreed to join the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. It is considered as benign pleural effusion by clinical diagnosis and imaging examination such as chest CT; 2. Less pleural effusion, ultrasound can not be located; 3. Severe pleural adhesion in the affected thoracic cavity; 4. Patient with serious cardiopulmonary diseases, or have invasive contraindications such as thoracentesis and pleural biopsy; 5. Patient or family member does not agree to join the investigator.

Design outcomes

Primary

MeasureTime frame
Diagnostic positive rate;

Countries

China

Contacts

Public ContactLuo Hu

First Affiliated Hospital of Army Military Medical University

luohucy@163.com+86 18623694525

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026