Colorectal Carcinoma
Conditions
Interventions
Light Anaesthetic Depth Group :General anaesthesia with intraoperative BIS targeted at 50
Deep Anaesthetic Depth Group:General anaesthesia with intraoperative BIS targeted at 35
Sponsors
Department of Anesthesiology, Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Elective laparoscopic colorectal surgery with an expected operative duration >= 2 hours; age between 18 and 65 years; ASA I-III; agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Pregnant or lactating women; inability to read, understand or communicate; previous history of esophageal or abdominal surgery; preoperative diagnosis of gastrointestinal obstruction; long-term exposure of opioids, NSAIDs or steroids; intraoperative mean BIS out of target range; stoma formation or conversion to laparotomy; combined organ resection during the operation; occurrence of severe perioperative complications; indwelling intragastric catheter intraoperatively according to decision from the surgeon
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of postoperative gastrointestinal dysfunction during hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-op Quality of Recovery;Serous I-FABP at 6 h post-op;Length of postoperative stay;Postoperative 30-day complications;Time to gastrointestinal function recovery;Another defined postoperative ileus; | — |
Countries
China
Contacts
Public ContactLiu Kexuan
Department of Anesthesiology, Nanfang Hospital, Southern Medical University
Outcome results
None listed