intrauterine adhension
Conditions
Interventions
Sponsors
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Women of childbearing aged 18 to 40 years old; 2) with regular menstruation and history of pregnancy; 3) patients with oligomenorrhea or secondary amenorrhea who were undergoing hysterscopic adhesiolysis for moderate and severe uterine adhesion.
Exclusion criteria
Exclusion criteria: 1) Previous operation history for intrauterine adhesion; 2) patients who have a previous history of uterine tuberculosis or are currently on drug treatment for tuberculosis; 3) patients with uncertain nature of endometrial lesions (such as endometrial dysplasia and carcinogenesis); 4) acute genital tract infection; 5) genital tract malformation; 6) severe hepatic and renal insufficiency: ALT>80U/L, Cr.>100 mol/L; 7) patients with a history of thrombosis or risk factors for thrombosis, such as APS (+), are not suitable for patients with high dose of estrogen; 8) platelet <80 x 10^9/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| menstrual quantity;thickness of endometrium around ovulational peried;intrauterine morphology;PDGF;TGF-ß;IGF;EGF;VEGF; | — |
Secondary
| Measure | Time frame |
|---|---|
| Colour and lustre of endometrium; | — |
Countries
China
Contacts
Public ContactShan Deng
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences,
Outcome results
None listed