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Effects of dexmedetomidine during comparable depth of anaesthesia as guided by bispectral index on motor evoked potential in patients undergoing spinal compression myelopathy surgery: a randomized controlled trial.

Effects of dexmedetomidine during comparable depth of anaesthesia as guided by bispectral index on motor evoked potential in patients undergoing spinal compression myelopathy surgery: a randomized controlled trial.

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018685
Enrollment
Unknown
Registered
2018-10-03
Start date
2018-09-15
Completion date
Unknown
Last updated
2018-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal compression myelopathy

Interventions

Group 1:constant infusion of dexmedetomidine propofol and remifentanil
Group 2:infusion of propofol and remifentanil

Sponsors

Honghui hospital, Xi'an Jiaotong University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients age between 18 and 70 years and ASA status from I to III; 2. Computed tomography(CT) or magnetic resonance image(MRI) studies showed spinal compression evidence; 3. Patients presented obvious spinal stenosis symptoms,like pain and numbness in limbs; 4. No strict gravity center, liver, kidney and blood system and other important organ diseases; 5. Sign informed consent.

Exclusion criteria

Exclusion criteria: (1) Combined injuries and old fractures; (2) A stroke history with residual neurological disorder; (3) Received spinal surgery or treatment before; (4) Alcohol or drug abusers; (5) Received wake-up test during decompression surgery; (6) No legal capacity or legal capacity is restricted; (7) The researchers considered it inappropriate to participate in any other circumstances of the trial.

Design outcomes

Primary

MeasureTime frame
the amplitude and latency of the motor evoked potential;modified Japanese Orthopaedic Association Scoring system;the amplitude and latency of the SEP;3-month follow-up neurological function scoring;

Secondary

MeasureTime frame
time to opening eye;toe-movement time;conscious status after anesthesia recovery;

Countries

China

Contacts

Public ContactLiu Tun

Department of Anesthesiology, Honghui hospital, Xi'an Jiaotong University,

405546707@qq.com+86 15249254721

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026