Squamous Cell Lung Cancer
Conditions
Interventions
Case series:Nab-P+CBP
Sponsors
Zhongnan Hospital, Wuhan University
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 Years to 75 years; 2. Performance status of 0 to 1 on the Eastern Cooperative Oncology Group (ECOG) Scale; 3. Previously untreated, histological documented, inoperable stage III squamous cell carcinoma of lung, excluding those with pericardial, pleural effusion, and those with contralateral hilar or contralateral supraclavicular lymph nodes; 4. Patients must have measurable disease according to RECIST criteria, and all detectable tumor can be encompassed by radiation therapy fields; 5. Patient must have adequate blood, liver, lungs and kidney function within the requirements of this study; 6. Female patients of child-bearing potential must test negative for pregnancy at the time of enrollment based on a serum pregnancy test. Male and female patients must agree to use a reliable method of birth control during and for 3 months following the last dose of study drug; 7. Patients must sign a study-specific informed consent form prior to study entry.
Exclusion criteria
Exclusion criteria: 1. Previous chemotherapy or previous biologic response modifiers for current lung cancer; 2. Patient has previously had thoracic radiation therapy; 3. Prior or concurrent malignancy except non-melanomatous skin cancer unless disease-free for five years or more; 4. Serious concomitant disorders that would compromise the safety of the patient, or compromise the patient's ability to complete the study, at the discretion of the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OS;ORR;LCR;Safety;QoL; | — |
Countries
China
Contacts
Public ContactConghua Xie
Department of Radiation and Medical Oncology, Zhongnan Hospital, Wuhan University
Outcome results
None listed