Relapsed/refractory acute myeoloid leukemia
Conditions
Interventions
Case series:No
Sponsors
Department of Hematology, Xinqiao Hospital, Army Medical University, Chongqing, People's Republic of China.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. To be able to understand and voluntarily sign an informed consent form; 2. Male or Female aged at least 18 years; 3. Patients with CD33 and/or CD123 positive refractory/relapsed AML according to FAB; 4. The estimated survival is over three months; 5. With detectable disease; 6. Unwilling or unable to receive hematopoietic stem cell transplantation or relapse after transplantation;. 7. Adequate main organ function: (1) Liver: ALT/AST 40 %. 8. Karnofsky =60 at study entry.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding female subject. 2. Drug abusers or 3. uncontrolled infection 4 weeks before enrolled. 4. Known positive for HIV or acute infectious hepatitis, type A, B or C 5. other primary tumor except for AML. 6. Serious autoimmune disease or mmune deficiency disorder. 7. Central nervous involvement 8. Serious psychiatric or psychological disorders. 9. Patients can not be enrolled which will be judged by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of remission; | — |
Secondary
| Measure | Time frame |
|---|---|
| Addvert effect; | — |
Countries
China
Contacts
Public ContactZhang Xi
Department of Hematology, Xinqiao Hospital, Army Medical University
Outcome results
None listed