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Natural History and Management Patterns of RCC associated with Von Hippel-Lindau Disease

Natural History and Management Patterns of RCC associated with Von Hippel-Lindau Disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018666
Enrollment
Unknown
Registered
2018-10-02
Start date
2018-09-29
Completion date
Unknown
Last updated
2018-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RCC associated with von Hippel-Lindau Disease

Interventions

Case series:Nil

Sponsors

Peking University First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Male and female aged at least 18 years; 2. renal tumor diameter <4cm and no obvious clinical symptoms,without clinical intervention; 3. The expectancy of patient's life is greater than or equal to 3 years; 4. The diagnosis of VHL related renal cancer was confirmed by genetic test; 5. Patients must accept written informed consent.

Exclusion criteria

Exclusion criteria: 1. renal tumor diameter >4cm, or <4cm and existing obvious clinical symptoms, even transfering requiring,must need to be clinical intervention; 2. Prior systemic therapy directed at advanced RCC is not allowed for patients; 3. Active malignant tumors without renal cell carcinoma, or history of other malignant diseases withen 5 years (excluding basal cell carcinoma and cervical carcinoma after active treatment); 4. Active, uncontrollable infectious disease; 5. Patients cant adhere to the follow-up.

Design outcomes

Primary

MeasureTime frame
linear growth rate;volume growth rate;volume doubling time;

Countries

China

Contacts

Public ContactGong Kan

Peking University First Hospital

gongkan_pku@126.com+86 13910394281

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026