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Correlation between Human epididymis protein 4 and interstitial lung disease in patients with rheumatoid arthritis

Correlation between Human epididymis protein 4 and interstitial lung disease in patients with rheumatoid arthritis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018637
Enrollment
Unknown
Registered
2018-09-30
Start date
2018-09-26
Completion date
Unknown
Last updated
2018-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

Gold Standard:Clinical outcome, meet the 2010 ACR/EULAR rheumatoid arthritis classification criteria.
protein&#32
4,anti-cyclic&#32
citrullinated&#32
peptide,&#32
rheumatoid&#32
factor

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) the diagnosis of RA in line with the 2010 American rheumatism association (ACR) for RA classification criteria; (2) perfect the relevant inspection, a complete medical records.The cases were divided into 2 groups, group by: referring to the 2000 ATS diagnostic criteria, proposed ILD will chest high-resolution CT findings of nodules, patchy shadow, changes in a funicular, pleural thickening and pulmonary fibrosis patients classified as group with pulmonary interstitial change group.the rest is non-pulmonary parenchymal changes RA group.

Exclusion criteria

Exclusion criteria: (1) with other connective tissue diseases; (2) in chronic kidney disease; (3) there are serious pulmonary infection, pulmonary tuberculosis, lung cancer and other lung diseases; (4) ovarian cancer, endometrial cancer and other gynecological malignant tumors.

Design outcomes

Primary

MeasureTime frame
Human epididymis protein 4;Imaging indicators of pulmonary fibrosis;creatinine;

Secondary

MeasureTime frame
anti-cyclic citrullinated peptide;rheumatoid factor;DAS28;

Countries

China

Contacts

Public ContactFan Quming

Affiliated Hospital of North Sichuan Medical College

fanqum@163.com+86 13550592716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026