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Correlation analysis of SLCO1B1 and APOE polymorphisms with atorvastatin lipid-lowering effect and toxic and side effects

Correlation analysis of SLCO1B1 and APOE polymorphisms with atorvastatin lipid-lowering effect and toxic and side effects

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018634
Enrollment
Unknown
Registered
2018-09-30
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperlipemia

Interventions

Case series:Nil

Sponsors

The Fifth Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults, the total cholesterol of fasting serum = 5.72mmol/L, or triglycerides = 1.70mmol/L, or low-density lipoprotein cholesterol = 3.12mmol/L, or high-density lipoprotein = 0.91mmol/L. No other lipid-lowering drugs were taken at the same time.

Exclusion criteria

Exclusion criteria: Abnormal liver and kidney function.

Design outcomes

Primary

MeasureTime frame
SLCO1B1 genotype;APOE genotype;

Countries

China

Contacts

Public ContactGuoyan Hu

The Fifth Affiliated Hospital of Guangzhou Medical University

hgychn@163.com+86 15002020600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026