Gastric ulcer with bleeding
Conditions
Interventions
Group 1:Lansoprazole for injection
Group 2:Omeprazole sodium for injection
Sponsors
Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 to 65 years old male and female; 2. Within 48 hours before enrollment, there are symptoms of upper hemorrhagic hemorrhage such as hematemesis and/or melena (positive fecal occult blood), and endoscopically determined to be bleeding caused by gastric ulcer, and it is not suitable for oral administration; 3, a single ulcer diameter = 2cm; 4. Negative pregnancy test; 5. The subject informed and voluntarily signed the informed consent form and agreed to participate in all visits, examinations and treatments as required by the protocol.
Exclusion criteria
Exclusion criteria: 1. hemoglobin normal upper limit); 9. severe cardiac insufficiency (NYHA grade 3 ~ 4), pulmonary insufficiency (symptoms of respiratory failure), malignant tumors, blood and hematopoietic system diseases; 10. combined with Barth syndrome, hypokalemia, hypocalcemia and acid-base balance disorders; 11. Those who have neurological or mental illnesses who are unable to cooperate or are unwilling to cooperate; 12. Suspect or have a history of alcohol or drug abuse, or other circumstances that reduce the likelihood of enrollment or complicate enrollment, according to the investigator's judgment; 13. Pregnant women, breastfeeding women and those with birth plans in the near future; 14. Those who have participated in other clinical trials within 3 months before the trial; 15. The investigator believes that it is not appropriate to participate in the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 72-hour hemostasis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| 72-hour rebleeding rate;Need to switch to other treatment rates during the course of treatment;Adverse event rate and incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactLiu Side
Nanfang Hospital, Southern Medical University
Outcome results
None listed