hypoproteinemia
Conditions
Interventions
Sponsors
Changxing People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) aged 18 years, male or female used high-dose tigecycline 100 mg or more per day; (2) Meet the sepsis diagnose standard of The Third International Consensus Definitions for Sepsis and Septic Shock ( Sepsis-3); (3) The presence of hypoproteinemia during the course of administration, ie serum albumin <25 g/L.
Exclusion criteria
Exclusion criteria: (1) patients who are allergic to or have a history of allergies to tetracyclines; (2) patients who refuse to participate the study, or who are unable to obtain blood samples due to unwillingness of the patient and the family of the patient; (3) unacceptable adverse reactions or Serious adverse events; (4) pregnant women; (5) patients with hypoproteinemia who were corrected before tigecycline.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak concentration;Trough concentrations;albumin; | — |
Secondary
| Measure | Time frame |
|---|---|
| age;sexual;weight;APACHE II score;Hospital stay time;clinical diagnosis;The site of infection;Procalcitonin;body temperature;leukocyte;C-reactive protein; | — |
Countries
China
Contacts
Public ContactLin Bin
Changxing People's Hospital
Outcome results
None listed