Gastroesophageal Reflux Disease
Conditions
Interventions
Gold Standard:gastroscope
24 hour PH-impedance monitoring
Index test:pepsin in saliva
Sponsors
the Second Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Completed gastroscope, with or without GERD symptoms: heartburn,regurgitation or GerdQ=8, and(or)with chronic cough, asthma, pharyngolaryngitis, tympanitis, nasosinusitis, glous hystericus and so on.
Exclusion criteria
Exclusion criteria: 1. With Zollinger-Ellison syndrome;Esophageal achalasia; Esophageal spasm; Esophagostenosis and other esophagus disease or esophageal surgery; 2. With a history of chronic disease,such as asthma or neurological disease; 3. With a history of malignancy; 4. Can not complete the study for any reason, such as language comprehension disorders, mental illness or can not tolerate the test; 5. With history of taking antiacid drugs or prokinetic agent a week before the test; 6. With anxiety symptoms(HAMA>14); 7. With a history of taking the medicine to relieve anxiety symptom,insomnias recently; 8. Under 18 years old; 9. In pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h PH-impedance monitoring;pepsin in saliva;gastroscope; | — |
Countries
China
Contacts
Public ContactXin He
Chongqing Medical University
Outcome results
None listed