infection and sepsis
Conditions
Interventions
Case series:Nil
Sponsors
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: adult patients with suspected community acquired pneumonia
Exclusion criteria
Exclusion criteria: 1. immunosupression; 2. current malignancy; 3. chest symptoms not solely accounted by pneumonia (cardiac failure, non-cardiogenic pulmonary oedema, suspected pulmonary embolism, suspected secondary acute respiratory distress syndrome); 4. prisoner/cognitive impairment/age less than 18 years; 5. hospitalization within 1 month; 6. whole blood transfusion within 1 month; 7. blood samples for gene expression could not be taken within 24 hours of admission.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| peripheral blood mononuclear cell genome wide expression differences uncomplicated pneumonia versus pneumonia with associated sepsis;peripheral blood mononuclear cell genome wide expression and association with organ dysfunction;peripheral blood mononuclear cell genome wide expression and association with clnical outcomes; | — |
Primary
| Measure | Time frame |
|---|---|
| feasibility of a genome wide expression study on patients with pneumonia; | — |
Countries
China
Contacts
Public ContactLowell Ling
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Outcome results
None listed