Respiratory disease
Conditions
Interventions
Group A:Use nutrition pump to input continuously in the daytime,the infusion rate increased gradually from 30ml/h to 60ml/h.The infusion was completed within 10-12h. The infusion rate was decreased wh
Group B:In normal physiological feeding time, interval 4h to 6h takes three periods
7:00~9:00
1200-14:00
17:00~19:00, Use nutrient pump to discontinue nutrient solution. The infusion rate was 30 ml/h to 60 ml/h on the first day, 90 ml/h to 120 ml/h on the second day,If there is no abnormality, Adjust to
Sponsors
Huzhou Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. conforming to the diagnostic criteria of chronic obstructive pulmonary disease (COPD) and type II respiratory failure; 2. having indications for non-invasive mechanical ventilation and estimated that the duration of non-invasive mechanical ventilation is longer than 3 days; 3. inability to swallow food orally or oral intake less than 50% of daily required nutrition; 4. Clear mind, be able to cooperate with communication and treatment; 5. Agde greater than or equal to 18 years old.
Exclusion criteria
Exclusion criteria: 1. ultrasonographic examination revealed abnormal organ morphology in digestive system; 2. having fstula, necrosis, obstruction, and surgery of gastrointestinal system; 3. Other serious medical conditions such as heart, liver and kidney dysfunction, cerebrovascular accident and ketoacidosis; 4. patients with unstable hemodynamics; 5. taking gastric motility drugs during the trial period; 6. BMI=30kg/m2; 7. need for changing diet or prescribing a specifc diet during the study; 8. pregnant woman.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single section area of antrum;Gastrointestinal tolerance; | — |
Secondary
| Measure | Time frame |
|---|---|
| motilin;Melanin; | — |
Countries
China
Contacts
Public ContactHua Feng
Huzhou Central Hospital
Outcome results
None listed