Chronic obstructive pulmonary disease
Conditions
Interventions
NPPV group:Noninvasive positive pressure ventilation
HFNC group: High-Flow Nasal Cannula
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with invasive respiratory failure due to type II respiratory failure; 2. Aged 18 to 85 years old; 3. Conforming to the diagnostic standard of COPD in the Ministry of health's "chronic obstructive pulmonary disease diagnosis and treatment standard (2011 Edition)"; 4. Patients can take care of themselves in the past 1 year; 5. AECOPD exacerbated by bronchoalveolar infection; 6. PIC window appeared after invasive ventilation and anti infection treatment.
Exclusion criteria
Exclusion criteria: 1. Informed consent is not available; 2. There are NPPV taboos: oral and facial injuries, poor sputum sputum excretion, unstable hemodynamics, etc.; 3. Short term poor prognosis,Death within 7 days of the big risk,Palliative care is under way; 4. Severe heart, brain, liver and kidney failure; 5. Cough reflex is extremely weak or sputum weakness when PIC window appears; 6. Tracheotomy patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Treatment failure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory parameters;Dyspnea score;Comfort score;Skin ulceration score;28 - day mortality rate; | — |
Countries
China
Contacts
Public ContactDingyu Tan
Northern Jiangsu People's Hospital
Outcome results
None listed