breast cancer
Conditions
Interventions
Group PR:patients received 30 ml of 0.25% ropivacaine + 2 ml normal saline to ultrasound-guided PECS II block
Group PD:patients received 30 ml of 0.25% ropivacaine + 1µg/kg dexmedetomidine to ultrasound-guided PECS II block
Group PN:patients received 30 ml of 0.25% ropivacaine + 20mg nalbuphine to ultrasound-guided PECS II block
Sponsors
First Affiliated Hospital of HeNan University
Eligibility
Sex/Gender
Female
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged 40 to 65 years old, unilateral breast surgery, women of American society of anesthesiologists (ASA) physical status I to III, modied radical mastectomy with or without axillary node dissection.
Exclusion criteria
Exclusion criteria: Regional blockade contraindications (infection, local anesthetic allergy, coagulopathy, use of anticoagulant drugs), the history of psychiatric illness and chronic pain, preexisting neuropathy involving the chest site, alcohol or opioids abusers, cardiopulmonary dysfunction, liver or renal impairment, morbid obesity (BMI >40 kg/m2).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time to first request for rescue analgesia;pain score at 2, 4, 8, 12 and 24 h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| the consumption of etomidate and remifentanil in the intraoperative room;opioid consumption at 24h after surgery;adverse events from postoperative 24h, such as nausia, vomiting;the effective number of presses (D1) and the actual number of presses (D2) were recorded about the PCIA pump to calculate D1/D2 for 24 hours after surgery;patient satisfaction rates for 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactHong Daoxian
First Affiliated Hospital of He'nan University
Outcome results
None listed