Breast cancer
Conditions
Interventions
Group C:0.375% ropivacaine 20ml
Group N: Nalbuphine 10mg+0.375% ropivacaine(20ml)
Group D :Dexmedetomidine 1µg /kg+ 0.375% ropivacaine(20ml)
Group ND:Dexmedetomidine 1µg /kg+ Nalbuphine 10mg+0.375% ropivacaine(20ml)
Sponsors
Department of Anesthesiology, First Affiliated Hospital of Henan University
Eligibility
Sex/Gender
Female
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: Females of American society of anesthesiologists (ASA) physical status I-II, BMI 18~24kg/m2, aged 35 to 65 years, who were scheduled for radical mastectomy will be included in this study.
Exclusion criteria
Exclusion criteria: History of breast surgery, incision site infection, coagulation dysfunction, drug allergy to local anesthesia, long-term history of opioids or antiemetic drugs, pregnant women, patients with central neuropathy, patients with liver and kidney dysfunction, patients with mental disorders, overweight patients (BMI > 30 kg / m2), patients with hypotension, and patients refusing to participate Add.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nume ricrating scale(NRS) pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay score;blood pressure;heart rate; | — |
Countries
China
Contacts
Public ContactZHENG Xiao-zhen
The First Affiliated Hospital of Henan University
Outcome results
None listed