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The study of the frequency of oral care with macrogenome and its effect on ventilator associated pneumonia

The macrogenome assay was used to determine a reasonable oral cleaning frequency and to verify its effect on ventilator associated pneumonia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018502
Enrollment
Unknown
Registered
2018-09-21
Start date
2018-09-22
Completion date
Unknown
Last updated
2018-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia/acute hemorrhagic stroke

Interventions

Group 1:Take oral care at an interval of X hours
Group 2:Take oral care at an interval of 12 hours

Sponsors

Dalian Municipal Central Hospital Affiliated Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Patients with acute hemorrhagic cerebral apoplexy admitted to ICU,after emergency craniocerebral operation,mainly included patients with acute subarachnoid hemorrhage and acute cerebral hemorrhage; 2. Aged 18 to 80 years old; 3. Expected/actual mechanical ventilation time > 48 hours.

Exclusion criteria

Exclusion criteria: 1. It is associated with chronic pulmonary infectious diseases, such as chronic asthmatic bronchitis, COPD, bronchiectasis, and empyema; 2. The incidence of hemorrhagic stroke is over 48 hours; 3. There was obvious aspiration after the onset of stroke; 4. Obvious gastric juice samples were sucked out during intubation; 5. CT examination before emergency operation showed obvious pulmonary atelectasis or pneumonia; 6. Patients who are participating in other clinical trials; 7. Suffering from severe intra-oral infectious diseases; 8. The researchers believe that other reasons are not suitable for clinical trial participants.

Design outcomes

Primary

MeasureTime frame
Ventilator associated pneumonia incidence;The onset time of ventilator-associated pneumonia;Patient mortality;The number of oral bacteria has increased;Serious dissonance of oral microflora composition;The relationship between oral microflora and upper gastrointestinal tract, lower respiratory tract and intestinal microflora;

Countries

China

Contacts

Public ContactCui Song

Dalian Municipal Central Hospital Affiliated Dalian Medical University

cuisong2008@qq.com+86 15541117225

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026