Parkinson disease
Conditions
Interventions
patients with parkinson's disease:no
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Selection criteria for patients with Parkinson's disease: (1) Clinically diagnosed with Parkinson's disease; (2) Age 40 or older; (3) Detailed personal information, clinical symptom information, and treatment information are available (4) Has a healthy spouse or sibling who lives together with the patient, and whose corresponding samples can be collected; (5) The patient's gender should be balanced as much as possible, That is, about 150, 150 cases for men and women, respectively; (6) If a patient have other diseases (intestinitis, dysentery, etc.) that have a great impact on the study, then this patient cannot be included until those diseases have healed. Health control group: (1) The optimal subjects are the spouses of Parkinson's patients, followed brothers and sisters living together; (2) Detailed personal information, clinical symptom information, and treatment information are available; (3) If a subject have other diseases (intestinitis, dysentery, etc.) that have a great impact on the study, then this subject cannot be included until those diseases have healed.
Exclusion criteria
Exclusion criteria: (1) Those whose Personal information, clinical symptom information or treatment information are incomplete. (2) Those who are Suffering from other diseases (intestinitis, dysentery, etc.) that have a greater impact on the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal microbial composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum microRNA expression level;Nasal microbial composition;Oral microbial composition; | — |
Countries
China
Contacts
Public ContactZhuo Li
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed