Congenitial heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Case group: children under 3 years old with simple congenital heart disease and their parents; control group: infants and their parents who were within 3 years of age without any birth defects
Exclusion criteria
Exclusion criteria: 1) children older than three years old; 2) children in the case group with other malformations; 3) children with malignant tumors; 4) unwilling to participate in the study; 5) parents with mental disorders or unable to complete the questionnaire for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal glycolipid metabolism gene polymorphism;Composition of intestinal flora;Diversity of intestinal flora;Infant cardiac specific transcription factor gene polymorphism;Paternal glycolipid metabolism gene polymorphism;Maternal cardiac specific transcription factor gene polymorphism;Paternal cardiac specific transcription factor gene polymorphism;Maternal plasma metabolomics; | — |
Countries
China
Contacts
Xiangya School of Public Health, Central South University