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Correlation between Glycolipid Metabolism Genes, Intestinal Flora and Congenital Heart Disease and Mutation and Expression of Cardiac Specific Transcription Factors

Correlation between Glycolipid Metabolism Genes, Intestinal Flora and Congenital Heart Disease and Mutation and Expression of Cardiac Specific Transcription Factors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018492
Enrollment
Unknown
Registered
2018-09-20
Start date
2018-10-01
Completion date
Unknown
Last updated
2018-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenitial heart disease

Interventions

Control group:None

Sponsors

Xiangya School of Publich Health, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Case group: children under 3 years old with simple congenital heart disease and their parents; control group: infants and their parents who were within 3 years of age without any birth defects

Exclusion criteria

Exclusion criteria: 1) children older than three years old; 2) children in the case group with other malformations; 3) children with malignant tumors; 4) unwilling to participate in the study; 5) parents with mental disorders or unable to complete the questionnaire for other reasons.

Design outcomes

Primary

MeasureTime frame
Maternal glycolipid metabolism gene polymorphism;Composition of intestinal flora;Diversity of intestinal flora;Infant cardiac specific transcription factor gene polymorphism;Paternal glycolipid metabolism gene polymorphism;Maternal cardiac specific transcription factor gene polymorphism;Paternal cardiac specific transcription factor gene polymorphism;Maternal plasma metabolomics;

Countries

China

Contacts

Public ContactJiabi Qin

Xiangya School of Public Health, Central South University

qinjiabi123@163.com+86 15974269544

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026