gastric cardia cancer
Conditions
Interventions
Case series:Oxaliplatin +5-FU intra-arterial infusion chemotherapy combined with doxorubicin-loaded microsphere embolization
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18-75 years old, gender is not limited; 2) It is confirmed by histopathological diagnosis that it is a newly diagnosed gastric cancer that cannot be surgically removed; 3) The expected survival period is greater than 3 months; 4) Physical status score ECOG = 1 point; 5) The pregnancy test for women of childbearing age must be negative; or both men and women need to agree to use effective contraception during the treatment period and for the following year.
Exclusion criteria
Exclusion criteria: 1) Can be surgically removed; 2) Poor coagulation function INR>1.5, or anticoagulant therapy or known bleeding disorder; 3) Unstable coronary heart disease or recent myocardial infarction (within one year); 4) Recent infections require antibiotic treatment; 5) Patients with pulmonary insufficiency (MVV%/VC%=50% and FVC%=40%); 6) White blood cells 2 mg / L); 8) AST and / or ALT > 5 times the upper limit of normal; 9) DSA showed that the tumor feeding artery was too slender and the intubation was unsuccessful; the arteriovenous fistula was not expected to be embolized by the microsphere; 10) A comorbid or social environment that can prevent a subject from following a research plan or even endangering patient safety; 11) The patient is accompanied by other primary tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease control rate;Objective response rate;Safety evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| QOL scores; | — |
Countries
China
Contacts
Public ContactWu Gang
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed