Advanced gynecological system tumors
Conditions
Interventions
Case series:Individualized chemotherapy
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female, age 18 to 75 years old; 2. Pathological histological examination of advanced gynecologic tumors, requiring anticancer drug chemotherapy; 3. Can take surgical resection or biopsy to obtain fresh tumor tissue; 4. With objective tumors in accordance with RECIST 1.1, CT/MRI can be used to evaluate the efficacy; 5. The ECOG score is 0~2, and the expected survival period must be =3 months; 6. In the case of postoperative subjects, the previous anticancer drug treatment (chemotherapy and / or targeted therapy) failed to enter the group for = 4 weeks, and the adverse reactions have basically recovered; 7. Subjects volunteered to participate, signed informed consent, good compliance, active treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Participate in other drug clinical studies at the same time; 2. Liver, kidney function and bone marrow hematopoietic function do not meet the requirements of chemotherapy; 3. Reluctant to use the anti-cancer drugs or regimens recommended by the investigator in combination with the results of this test for subsequent chemotherapy after the previous treatment failure; 4. Those with severe uncontrolled acute infections or major organ diseases; 5. Women who are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR;DCR; | — |
Countries
China
Contacts
Public ContactMeng yuanguang
Chinese PLA General Hospital
Outcome results
None listed