diabetes
Conditions
Interventions
Group 1:complex probiotic intervention
Group 2:Placebo
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. Has been diagnosed with type 2 diabetes according to the standardization of the World Health Organization ( WHO) 1999 ; 3. Are treated by Lifestyle intervention alone or Lifestyle intervention plus metformin (Maintain a stable dose of drugs at least 30 days before the trial); 4. HbA1c 6.5% to 9%; 5. To be informed and volunteer to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Type 1 diabetes; 2. smoking; 3. Those who are pregnant or nursing; 4. using insulin; 5. presence of 1 or more of the following complications: diabetic retinopathy, microalbuminuria or nephropathy; 6. Severe chronic or acute inflammatory disease, gastrointestinal tract, Liver, kidney disease, short bowel syndrome, allergies,or immune deficiency disorder; 7. Severe coronary heart disease, myocardial infarction or stroke, cancer; 8. Taking anti-obesity drugs or slimming drugs and other dietary supplements (fish oil, probiotics, prebiotics, multi vitamins).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood glucose and glycosylated hemoglobin,gycated serum protein;blood lipid; | — |
Secondary
| Measure | Time frame |
|---|---|
| oxidative stress level;Inflammatory factors level;intestinal flora; | — |
Contacts
Public ContactLiyong Chen
Shandong Provincial Hospital
Outcome results
None listed