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The effect of different concentrations of heparin sealing liquid on thrombosis after Peripherally inserted central catheter catheterization in malignant tumor patients: A prospective, single-blind, randomized, controlled study

The effect of 10U/ml and 50U/ml heparin sealing liquid compared with saline on thrombosis after Peripherally inserted Central Catheter catheterization in tumor patients: A prospective, single-blind, randomized, controlled study

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018391
Enrollment
Unknown
Registered
2018-09-14
Start date
2017-07-01
Completion date
Unknown
Last updated
2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute embolism and thrombosis of deep veins of up extrem

Interventions

Group 1:10 U/ml heparin solution
Group 2:50 U/ml heparin solution

Sponsors

Guangzhou First people's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Patients aged at least 18 years and volunteered to participate in the study; 2) Patients were with malignant tumor in pathologic diagnosis, and planned to have intravenous chemotherapy; 3) The placing of PICC was practiced by nurses specialized in intravenous treatment with qualification certificate in the First People's Hospital of Guangzhou; 4) Patients received treatment in our hospital, and the PICC maintenance was performed in the catheterization clinic of our hospital during the treatment interval.

Exclusion criteria

Exclusion criteria: 1) Patients with severe cognitive impairment who are unable to cooperate; 2) Patients who did not sign an informed consent form; 3) Patients with serious complications and other serious chronic diseases; 4) Patients who were not maintained in our hospital and were not able to be tracked; 5) Patients who had thrombosis immediately after catheterization; 6) Patients with hypercoagulable status and patients with open-ended PICC catheter.

Design outcomes

Primary

MeasureTime frame
Incidence of Upper extremity venous thrombosis (%);

Secondary

MeasureTime frame
The time interval from PICC catheterization to thrombus;The severity of thrombosis, including grade I, grade II, and grade III;

Countries

China

Contacts

Public ContactZhimin Wang

Guangzhou First People's Hospital

wzm8882@qq.com+86 13503008308

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026