Breast Cancer
Conditions
Interventions
concurrent group:concurrent chemoradiotherapy
sequential group:chemotherapy followed by radiotherapy
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Female aged 18 and 70 years old; 2. ECOC 0-2 or KPS =70; 3. Treated with breast-conserving surgery; 4. Pathologically diagnosed with invasive breast cancer patients; 5. Chemotherapy and radiotherapy are needed after surgery; 6. No major organ dysfunction; 7. No obvious side effects during chemotherapy before radiotherapy; 8. Patients voluntarily participate in study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who had not completed postoperative adjuvant chemotherapy as scheduled; 2. Could not tolerate concurrent chemoradiotherapy with severe comorbidities or other diseases; 3. Have any other medical history or may interfere the clinical results or increase the patient's risk according to the researcher's judgment; 4. Have serious basic diseases; 5. Have obvious side effects during chemotherapy before radiotherapy; 6. Patients who refused or were unable to sign the informed consent form; 7. With any other circumstances that the investigators consider to be unsuitable for participation in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease free survival;overall survival;RTOG score; | — |
Secondary
| Measure | Time frame |
|---|---|
| local regional control rate;total survival rate;the length of hospital stay;hospital cost; | — |
Countries
China
Contacts
Public ContactGong Yiping
Renmin Hospital of Wuhan University
Outcome results
None listed