Effects of Low-dose Ketamine on MACBAR of Sevoflurane in Laparoscopic Cholecystectomy Surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800018344

Enrollment

Unknown

Registered

2018-09-12

Start date

2018-10-01

Completion date

Unknown

Last updated

2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic Cholecystectomy Surgery

Interventions

Group 1:ketamine 5ug·kg/min

Group 2:ketamine 10ug·kg/min

Group 3:ketamine 20ug·kg/min

Group 4:ketamine 0ug·kg/min

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status I or II; Aged 18 – 65 years; scheduled for electivelaparoscopic cholecystectomy surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: BMI 30 kg/m2; Have mental illness; A history of substance abuse or alcoholism;Have a heart disease, lung disease, liver disease, kidney disease and encephalopathy history; Use of local anesthetics or use preoperativedrugs have an effect on cardiovascular system.

Design outcomes

Primary

Measure	Time frame
Heart rate; mean arterial pressure;	—

Countries

China

Contacts

Public ContactFaping Tu

tfpnc@163.com+86 1380827083

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026