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Comparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgaris

Comparative study for salicylic acid vs glycolic acid in the treatment of mild-to-moderate acne vulgaris: a prospective, randomized, split-face trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018343
Enrollment
Unknown
Registered
2018-09-12
Start date
2018-09-18
Completion date
Unknown
Last updated
2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris

Interventions

Group 1:Salicylic acid peel
Group 2:glycolic acid peel

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Either sex aged 18-45 years (inclusive); 2. mild-to-moderate facial acne vulgaris, with total lesion conut less than 100, inflammatory lesion count between 5-40, no cyst or nodule; 3. no treatment received in the past 3 months.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or breastfeeding; 2. other physical or mental disease; 3. secondary acne and sever acne; 4. skin lesions (herpes, warts, wound et al) on face; 5. patient who has to take anti-acne medicine during the trial, eg: antibiotics, oral contraceptives; 6. patient who has received laser treatment and dermabrasion; 7. known allergy to glycolic acid or salicylic acid; 8. patient who is not able to avoid sunlight.

Design outcomes

Primary

MeasureTime frame
percentage change in Inflammatory lesion count;

Secondary

MeasureTime frame
percentage change in non-Inflammatory lesion count;percentage change in total lesion count;incidence of adverse event;skin physiological function;subject global change assessment;Investigator’s Static Global Assessment;

Countries

China

Contacts

Public ContactJiang Xian

West China Hospital, Sichuan University

jennyxianj@163.com+86 18980601693

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026