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Research for the relationship between CYP2C19, PON1 gene polymorphisms and the clopidogrel resistance of patients with coronary heart disease in Jin-Hua

Research for the relationship between CYP2C19, PON1 gene polymorphisms and the clopidogrel resistance of patients with coronary heart disease in Jin-Hua

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018316
Enrollment
Unknown
Registered
2018-09-11
Start date
2018-09-20
Completion date
Unknown
Last updated
2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coranary heart disease patiants

Interventions

Case series:Null

Sponsors

Jin Hua Municipal Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged at least 18 years; 2. patients who have been diagnosised as coronary heart disease through coronary angiography and need undergo PCI; 3. Routine postoperative clopidogrel treatment after PCI.

Exclusion criteria

Exclusion criteria: 1. patients who have been sensitive or intolerance to Aspirin or clopidogrel; 2. patients who have A history of visceral hemorrhage or stroke within six months; 3. patients with severe coagulation dysfunction or hepatic disease; 4. patients who will undergo surgery or contraindications for antiplatelet therapy; 5. patients with end-stage disease; 6. patients who were not born in Jin Hua and not Han population.

Design outcomes

Primary

MeasureTime frame
platelet aggregation;CYP2C19 2*, 3*genotype;PON-1 genotype;—

Countries

China

Contacts

Public ContactZhang Zhaowei

Jinhua Central Hospital

392814297@qq.com+86 15058504824

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 28, 2026