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The central mechanism of the soothing-stagnant-liver-qi therapy treating for psychologic ED might associate with regulating the brain networks especially the cerebral activities of limbic system the organogenic erectile dysfunction

The central mechanism of the soothing-stagnant-liver-qi therapy treating for psychologic ED might associate with regulating the brain networks especially the cerebral activities of limbic system the organogenic erectile dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018301
Enrollment
Unknown
Registered
2018-09-10
Start date
2018-09-25
Completion date
Unknown
Last updated
2018-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Erectile dysfunction

Interventions

Chinese herbal treatment group:chaihu shugan powder
Western medicine treatment group:tadalafil
The placebo group:palcebo

Sponsors

Zhang Pei-Hai
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. absence of organic ED; 2. normal morning and nocturnal penile erection rated by the Nocturnal Penile Tumescence using RigiScan test (the tool of rigiscan used in our study was just confirmatory; 3. all patients enrolled in this study underwent duplex doppler ultrasonography with PSV measurements before and after ICI of prostaglandin. Moreover, all patients were enrolled in this study after (1) a detailed history taking (including medical history, sexual history, and relevant drug history); (2) basic laboratory tests; (3) detailed psychophysical status evaluation including the level of depression rated by the 17-item Hamilton Rating Scale for Depression(HAMD-17) and the level of anxiety rated by the 14-item Hamilton Rating Scale for Anxiety (HAMA-14), and (iv) sexual functioning assessed by the International Index of Erectile Function(IIEF).

Exclusion criteria

Exclusion criteria: 1. serious psychiatric, neurological,cardiovascular, respiratory, gastrointestinal or renal diseases; 2. urological surgery; 3. organic brain disorder; 4. drug or alcohol dependence; 5. use of any psychoactive medication and other medications that might affect sexual function during the previous 30 days; 6. any contraindications toundergo an MRI scan.

Design outcomes

Primary

MeasureTime frame
functional magnetic resonance imaging (fMRI);

Countries

China

Contacts

Public ContactZhang PeiHai

Chengdu University of TCM

zhangpeihai@126.com+86 18908173378

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026