gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients under 18-75 years old undergoing laparoscopic distal gastric cancer resection without preoperative neoadjuvant therapy.
Exclusion criteria
Exclusion criteria: 1. Participating in another concurrent intervention trial; 2. Patient have complete pyloric obstruction; 3. Known hypersensitivity or allergy to caffeine/coffee or tea; 4. American Society of Anesthesiologists (ASA) Physical Status Score of IV or V; 5. Alcoholism or drug abuse; 6. Previous extensive abdominal surgery (any open or laparoscopic abdominal surgery except laparoscopic appendectomy, cholecystectomy, or hernia repair); 7. Inflammatory bowel disease; 8. Cardiac insufficiency more than III grade (NYHA); 9. Intake of opioid analgesics, or steroids > 5 mg/day for = 7 days before surgery; 10. Long term history of intake of glucocorticoid and gastrointestinal motility drugs; 11. Under anti-depressive medication; 12. Patient with primary diabetes and impaired glucose tolerance, hyperthyroidism and hypothyroidism; 13. Severe obesity (BMI > 32) and severe malnutrition (BMI < 15); 14. History of constipation; 15. Pregnancy, lactation, or childbearing potential without using adequate contraception.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| gastrointestinal function recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| occurrence of postoperative complications;postoperative hospital stays;Hospital expenses;visual analog pain (VAS) scales;fatigue scores;inflammatory factors; | — |
Countries
China
Contacts
Affiliated Hospital of Qingdao University