Intrauterine adhesion
Conditions
Interventions
stem cell group:umbilical cord mesenchymal uterine cavity injection with stem cells/chitosan-collagen
control group :uterine cavity injection with chitosan-collagen
Sponsors
Women's Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) 30 patients with severe intrauterine adhesions diagnosed by hysteroscopy; 2) aged 20 to 40 years old; 3) transvaginal ultrasound detection of follicles before hysteroscopic surgery, in endometrial hyperplasia Period, the thickness of the double inner membrane is less than 7mm; 4) there are fertility requirements.
Exclusion criteria
Exclusion criteria: 1) combined reproductive system malformations, such as mediastinal uterus; 2) combined with other diseases of the reproductive system, such as uterine fibroids, adenomyosis, etc.; 3) severe internal surgical diseases with pregnancy contraindications; 4) combined with Artificial cycle treatment contraindications; 5) history of tuberculosis in the reproductive system.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of intrauterine adhesion;endometrial thickness;pregnancy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Molecular biomarkers of endometrium; | — |
Countries
China
Contacts
Public ContactRuijin Wu
Women's Hospital, Zhejiang University School of Medicine
Outcome results
None listed