PDR
Conditions
Interventions
Group 2:general anesthesia combine with preoperative anti-VEGF
Group 3:general anesthesia combine with intraoperative anti-VEGF
Group 4:local and targert-controlled anesthesia
Group 5:local and targert-controlled anesthesia combined with preoperative anti-VEGF
Group 6:local and targert-controlled anesthesia combined with intraoperative anti-VEGF
Sponsors
The Eye Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Aged =18 years old; 2) type 1 or type 2 diabetes; 3) tractional vascular detachment caused by retinal fibrovascular proliferation; 4) vitreous hemorrhage, B-ultrasound suggests tractional retinal detachment.
Exclusion criteria
Exclusion criteria: 1) Complete or partial completion of panretinal photocoagulation; 2) History of previous injections of anti-VEGF drugs; 3) combined with rhegmatogenous retinal detachment; 4) iris neovascularization, anterior chamber neovascularization and neovascular glaucoma;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative bleeding score; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of Intraoperative electrocoagulation;Intraoperative iatrogenic hole;Surgical difficulty score;Early postoperative bleeding;Late postoperative bleeding;Postoperative macular edema; | — |
Contacts
Public ContactYong Wei
The Eye Hospital of Wenzhou Medical University
Outcome results
None listed