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Positive End Expiratory Pressure Titrated by Transpulmonary Pressure in Patients with Acute Respiratory Distress Syndrome

Positive End Expiratory Pressure Titrated by Transpulmonary Pressure in Patients with Acute Respiratory Distress Syndrome

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018215
Enrollment
Unknown
Registered
2018-09-05
Start date
2018-10-01
Completion date
Unknown
Last updated
2018-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Interventions

Group 1:PEEP Titrated by Transpulmonary Pressure
Group 2:PEEP Guided by The Best Compliance

Sponsors

Gansu Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 - 75 years old; 2. There is no gender limit; 3. Patients were included in the study if they had ARDS according to the BoLin definitions.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients with unstable hemodynamics are expected to die 24 h; 3. Bronchopleural fistula, esophageal obstruction, esophageal perforation, severe esophageal variceal bleeding, and upper digestive tract surgery; 4. Thoracic deformity and diaphragmatic hernia; 5. Untreated pneumothorax, large amount of pleural effusion; 6. Severe heart, liver, kidney and other organ failure; 7. Other patients who are not suitable for placement of esophageal balloon catheter.

Design outcomes

Primary

MeasureTime frame
Pa02/Fi02;—

Secondary

MeasureTime frame
Rrespiratory-system Compliance;28-Day mortality;180-Day mortality;Ventilator Days;ICU hospitalization days;Hospitalization days;—

Countries

China

Contacts

Public ContactYuan Yuan

Gansu Provincial Hospital

lanzhouyy@163.com+86 0931-8281460

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026