thoracic disease
Conditions
Interventions
NIVATS group:Paravertebral nerve block + laryngeal mask general anesthesia + spontaneous breathing
GAVATS group:General anesthesia with double-lumen tube and single-lung ventilation as routine
Sponsors
Shanghai Chest Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA I or II, age 18 to 70 years old; 2. Elective thoracoscopic lung resection (wedge cutting, segment cutting, leaf cutting); 3. Male or female, postoperative hospitalization for at least 3 days; 4. Pulmonary function tests are generally normal.
Exclusion criteria
Exclusion criteria: 1. Difficult airway risk, Mallampati score = 3; 2. Obesity, body mass index BMI>28kg/m2; 3. Hemodynamic instability; 4. Coagulopathy, INR>1.5; 5. Respiratory infection, persistent cough, lung prurulent secretions, risk of reflux; 6. With neurological diseases; 7. Extensive pleural adhesions or history of chest surgery; 8. Poor lung function before surgery, hypoxemia PaO2 50mmHg; 9. Absolute indication for lung isolation; 10. Contraindications for regional block or local anesthesia; 11. Expected prolonged surgery,great surgical trauma,expected to open thoracotomy,poor team work; 12. Patients are reluctant to non-tracheal intubation anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glottal injury incidence;postoperative sore throat;hoarse voice;Airway mucosal injury biomarker;Postoperative cough score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung collapse score;Intraoperative cough;postoperative Pulmonary complications;Recovery time after anesthesia;SF12 score;Pain score (VAS, PH);Hospital stay;conversion to orotracheal intubation; | — |
Countries
China
Contacts
Public ContactJingxiang Wu
Shanghai Chest Hospital, Shanghai Jiao Tong University
Outcome results
None listed