twins
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age between 18-50 years old; 2) Twin pregnancy; 3) Fetal survival at 11-13 weeks of pregnancy; 4) Understand and sign informed consent, willing to provide detailed medical history information
Exclusion criteria
Exclusion criteria: 1) Failure to sign consent, cognitive or intellectual disability, inability to understand and write Chinese; 2) singleton pregnancy or triplet and above pregnancy; 3) no fetal heartbeat at NT screening (abortion) )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Uterine artery pulsatility index;Placental growth factor;sFlt-1; | — |
Countries
China
Contacts
the Affiliated Drum Tower Hospital of Medical School of Nanjing University