type 2 diabetes-associated periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Subjects are informed and consent; 2) With a clinical diagnosis of chronic periodontitis,probing depth=5mm,attachment loss=3mm; 3) Meet the diagnostic criteria of diabetes mellitus in 1999 (fasting blood glucose=7.0mmol/L or 2H blood glucose=11.1 mmol/L, fasting blood glucose=10.0mmol/L); 4) Subjects have not received periodontal therapy in the previous 6 months; 5) Subjects aged 18-60 years old,female or male.
Exclusion criteria
Exclusion criteria: 1) Severe complications of diabetes; 2) Aggressive periodontitis; 3) Periodontal abscess; 4) History of periodontal therapy or usage of antibiotics or immunosuppressor within 6 months; 5) The presence of pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical attachment level;Probing depth;Attachment loss;Bleeding Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-1ß;bFGF; | — |
Countries
China
Contacts
Shanghai Jiao Tong University Affiliated Sixth People’s Hospital