Postoperative delirium
Conditions
Interventions
Sponsors
The Third Central Hospital of Tianjin
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: Sixty patients, aged 65-85 years, BMI 18-25 kg/m2, ASA physical status II or III, scheduled to undergo elective laparoscopic cholecystectomy, were to be scored according to Montreal cognitive assessment (MoCA), minimental state examination (MMSE), dementia scale (CDR) and daily living ability scale (ADL) to identify patients with MCI before the surgery.
Exclusion criteria
Exclusion criteria: The patients with neurologic diseases (such as vascular dementia) affecting cognitive function, severe liver and renal insufficiency, coronary artery, peripheral artery or cerebrovascular diseases, autoimmune diseases, recent taking of tranquilizers, antidepressants or immunosuppressive drugs, etc., and the history of craniocerebral trauma and alcoholism will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-10;TNF-a;HO-1;CAM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery time of general anesthesia; | — |
Countries
China
Contacts
Public ContactHaiyun Wang
Tianjin Third Central Hospital
Outcome results
None listed