LH based flexible GnRH antagonist protocol in PCOS patient undergoing in vitro fertilization and embryo transfer: a randomized controlled trial

Application of a more flexible GnRH antagonist protocol in PCOS patient undergoing in vitro fertilization and embryo transfer

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800018129

Enrollment

Unknown

Registered

2018-08-31

Start date

2018-10-01

Completion date

Unknown

Last updated

2020-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Group 1:traditional flexible GnRH antagonist protocol

Group 2:LH based flexible GnRH antagonist protocol

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Women aged 23-35 years; 2. PCOS diagnosed with Rotterdam standards; 3. BMI18-28kg/m2; 4. The subjects must be volunteers and sign informed consents in person or by the legal representative.

Exclusion criteria

Exclusion criteria: 1. ultrasound or hysteroscopy indicated intrauterine or endometrial lesion, including uterine malformation, endometrial polyp, hyperplasia, intrauterine adhesion, etc; 2. endometriosis, adenomyosis; 3. medical comorbidities like diabetes mellitus

Design outcomes

Primary

Measure	Time frame
Cumulative ongoing pregnancy rate per cycle;	—

Secondary

Measure	Time frame
clinical pregnancy rate;the OHSS rate;good quality embryos rate;	—

Countries

China

Contacts

Public ContactYuan Li

Beijing Chao-Yang Hospital affiliated to Capital Medical University

sdliyuan@126.com+86 18611676757

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026