early glottic cancer
Conditions
Interventions
Group 1:Transoral CO2 laser laryngectomy
Group 2:transoral low-temperature radiofrequency ablation laryngectomy
Sponsors
Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with laryngeal cancer are first-diagnosed, which is pathologically confirmed as squamous cell carcinoma; 2. The clinical type was glottic cancer and the tumor stage was between Tis and T2N0M0; 3. The general condition of patients can be tolerated by the treatment and general anesthesia. No surgical contraindications were found; 4. Patients are volunteered to participate in the project and sign up the informed consent (approved by the hospital ethics committee).
Exclusion criteria
Exclusion criteria: 1. Patients with previous laryngeal surgery; 2. Patients who refuse to accept the treatments; 3. Patients with poor general condition can't tolerate the surgery and general anesthesia; 4. Patients with limited mouth opening, inability to recline or severe cervical spondylosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tumor recurrence rate of 1 year;survival rate;voice quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| medical cost;The length of hospitalization;6/5000 Intraoperative blood loss; | — |
Countries
China
Contacts
Public ContactMingliang XIANG
Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed