Total hip arthroplasty
Conditions
Interventions
A:Oral 2g TXA two hours before surgery
B:Oral 2g TXA 2 hours before surgery and 2g TXA 2 hours after surgery
C:Oral 2g TXA two hours before surgery, 2g TXA orally after 2.6.10 hours
Sponsors
West China School of Medicine, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with primary unilateral anterior total hip arthroplasty due to end-stage osteoarthritis, femoral head necrosis (Ficat stage III-IV), and type I-II hip dysplasia.
Exclusion criteria
Exclusion criteria: Hip joint stiffness, history of previous hip surgery, anemia, female 30 or <20, age less than 18 or 80 years old, American Society of Anesthesiologists (ASA) 4 or 5 patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hidden Blood Loss;Total Blood Loss;Maximum hemoglobin decline;Blood transfusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative inflammatory index (IL-6, CRP);Postoperative VAS Pain score;Postoperative Hip swelling Rate;Range of Hip flexion and abduction;Postoperative Harris Score;Length Of Stay;Postoperative compliance; | — |
Countries
China
Contacts
Public ContactGuanglin Wang
West China School of Medicine, West China Hospital, Sichuan University
Outcome results
None listed