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Quantification of arteriosclerotic cerebral small vessel disease by multi-mode magnetic resonance imaging

Quantification of arteriosclerotic cerebral small vessel disease by multi-mode magnetic resonance imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018097
Enrollment
Unknown
Registered
2018-08-30
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular disease

Interventions

control group:none
hypertension group I level:none
hypertension group II level:none
hypertension group III level:none

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) normal control group (n = 50), selected age matched with patients with cerebellar small vessel disease volunteers without previous nervous system and traumatic diseases; (2) patients with hypertension (n = 50), confirmed by cardiovascular and neurologists (phase I), blood pressure control is stable and no cerebrovascular accident; (3) hypertension (n = 50), through heart and blood. Tube and neurologists diagnosed (stage II), and no cerebrovascular accidents; (4) Hypertension and / or no cerebrovascular accidents (n = 50), diagnosed as hypertension (stage III), after treatment stable.

Exclusion criteria

Exclusion criteria: 1. There are metal implants and claustrophobia in the body; 2. The image quality is unsatisfactory and quantitative analysis can not be completed; 3. There are patients with massive cerebral infarction, cerebral hemorrhage, brain tumor, inflammatory demyelinating disease and other nervous system diseases.

Design outcomes

Primary

MeasureTime frame
white matter hyperintensities;micro-bleed;encephalatrophy;Cerebral vascular morphology;diffusion correlation measurement;

Countries

China

Contacts

Public ContactLi Yue hua

Shanghai Sixth People's Hospital

liyuehua312@163.com+86 021-24058619

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026