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The Study and Clinical Efficacy Evaluation of Yiqi Jiedu Tongluo Decoction combined with EGFR-TKI Delays Targeted Drug Resistance in Advanced Non-small Cell Lung Cancer

The Study and Clinical Efficacy Evaluation of Yiqi Jiedu Tongluo Decoction combined with EGFR-TKI Delays Targeted Drug Resistance in Advanced Non-small Cell Lung Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018087
Enrollment
Unknown
Registered
2018-08-29
Start date
2019-05-01
Completion date
Unknown
Last updated
2018-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer

Interventions

treat group :Yiqi Jiedu Tongluo decoction+RGFR-TKI

Sponsors

Shanghai Pulmonary Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. patients with pathologically confirmed NSCLC; 2. patients with stage IIIB-IV; 3. age = 18 years; 4. estimated survival = 3 months; 5. There are no serious diseases such as heart, liver, kidney, and blood system. Laboratory examination before enrollment must meet the following conditions: white blood cell WBC=3.5×10^9/L, hemoglobin Hgb=90g/L, platelet=100×10^9/L, bilirubin=1.5ULN, alkaline phosphatase (AP), Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) = 2.5ULN, INR = 1.5, creatinine = 1.5ULN; 6. The patient volunteered to participate in the study and signed an informed consent form prior to enrollment.

Exclusion criteria

Exclusion criteria: 1. those with other tumor diseases; 2. those who have received targeted therapy (previously who have undergone surgery, radiotherapy, or chemotherapy, the treatment can be entered 24 weeks after the start of the study); 3. Those with a history of severe cardiovascular disease (including unstable angina, myocardial infarction, congestive heart failure > in NYHA class II); 4. pregnant or lactating patients; 5. people with a history of mental illness that is difficult to control.

Design outcomes

Primary

MeasureTime frame
ctDNA;immune indexs;CEA;D-dimer;

Countries

China

Contacts

Public ContactLixin Wang

Shanghai Pulmonary Hospital

wlx1126@hotmail.com+86 18917962300

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026